Tuesday, December 24, 2019
Case Study Hotel And Resort Crisis Action Plan - 956 Words
Keller Graduate School of Management Colonnade Hotel and Resort Crisis Action Plan Aaron Buenaventura Managerial Communication MGMT 550 Professor: Bonnie Adams 8/13/2015 Introduction The hospitality industry offers sensational occasions for travelers to experience. With this unique opportunity comes great responsibility, not only for our hotel guests or any visitor to our hotel, but also our company. This crisis action plan is designed to provide a framework for a practical communications system that may be adaptable for any crisis situation. This will be a living document ââ¬â continually updated as we strive for continuous improvement and as we grow with experience. Company Core Values #1 ââ¬â Our guests are number 1 #2 ââ¬â We strive for excellence #3 ââ¬â We embrace change Crisis Action Procedure Each crisis is unique, and it is not reasonable to expect to use a strict set of procedures in response to every crisis situation. Monitoring and Crisis Identification It is everyoneââ¬â¢s duty to continuously observe and analyze daily events. Crisis issues can usually be placed in one of two categories: 1) Manmade 2) Natural. Examples of manmade crisis are things like work violence, building vandalism, stairwell accidents, operator error, staff negligence, defective equipment, poor planning and scheduling, strikes, fire, and illness such as food poisoning. Examples of natural crisis are things such as weather, earthquakes and communicable disease. Information Gathering It isShow MoreRelatedThe Taj Mahal Palace and Power Hotel in Mumbai1755 Words à |à 7 PagesTata (founder of the Taj Group), The Taj Mahal Palace and Tower, Mumbai was opened in 1903 as the first hotel by the Taj Group and representative of Indiaââ¬â¢s rich heritage. It is a flagship hotel of Taj Hotels Resorts and Palaces which is a part of The Indian Hotels Company (IHCL) and contains 560 rooms and 44 suits. Situated adjacent to the landmark, Gateway of India at waterââ¬â¢s edge, the hotel offers east access to numerous local tourist destinations and official agenices.For more than a centuryRead MoreA Study of Tourism in Thailand21369 Words à |à 86 PagesIntroduction 1.1 Introduction This dissertation is about small to medium sized hotels businesses in Thailand. It will investigate their use of events as a marketing tool. The study conducted online surveys by selected hundred hotels from the travel trade show in Thailand, 2010. Moreover, two selected hotels are interviewed by telephone and through telephone the results will be analysesis and compared asinto two case studies. The findings of the two different methods will be analysed in order to compareisonRead MoreChange Management- Shangri-La 20003516 Words à |à 15 Pagesin Shangri-La. The case study undertaken in Shangri-La, Kowloon (hereinafter referred to as ââ¬Å"KSLâ⬠) is used as an example to help us to illustrate the issues that the management of Shangri-La encountered. We will also discuss the possible handling approaches of those issues. Background Shangri-La Hotels and Resorts have been established in Singapore by Malaysian-Chinese tycoon Robert Kuok in 1971. In the early stage of the business, the management of Shangri-La Hotels was contracted withRead MoreCase Study: Fundamentals of Management3451 Words à |à 14 PagesFaculty of Hospitality Tourism Studies Fundamentals of Management Fundamentals of Management Case Study Mariyam Reema AbdulHameed (SID: 32601) Page 1 of 15 Faculty of Hospitality Tourism Studies Fundamentals of Management Table of Contents Introduction .................................................................................................... 3 Performance review ...................................................................................... 5 Mintzbergââ¬â¢s Managerial rolesRead MoreHyatt Regency Paper8223 Words à |à 33 Pagesenvironment and how it is affecting the hotel industry, and then will be preceded by a corporate level and business level strategy analysis. The company that will be the subject of the paper will be Hyatt Global Corporation, and its brand, Hyatt Regency. In the PESTE (Political, Economic, Socio-Cultural, Technological, Ecological) analysis the group discovered many circumstances that are currently affecting the hotel industry. The threat of terrorism, the financial crisis, the evolution of travelers, theRead MoreEssay Mgm Resorts International Case Study8629 Words à |à 35 PagesCase Study: MGM Resorts International 27 February 2013 Table of Contents Key Dates and General History 3-5 Environmental Analysis 5-7 Porter Analysis 7-9 Marketing Strategy 9-12 Competitor Analysis (SWOT) 12-18 Company Analysis (SWOT) 18-20 Financial Analysis 21-22 Future Trends 22-23 Recommendations 23-25 ConclusionRead MoreSpains Financial Crisis2845 Words à |à 12 PagesCASE 1 Spainââ¬â¢s in trouble Spain started facing economic troubles since 2008 global crisis. Financial crisis caused a huge crash in the property market and significant losses at its banks. These days Spainââ¬â¢s citizens take part in polls in Galicia and Basque regions. Galiciaââ¬â¢s PM Mariano Rajoy lost part of national support due to his austerity measures. Basque countryââ¬â¢s Socialist Party met opposite influence from Basque Nationalist Party. Unemployment rate in Spain grew to 25% in some regions likeRead MoreDisney in Asia, Again6524 Words à |à 27 PagesPace University DigitalCommons@Pace Case Studies Lubin School of Business 3-1-2002 Disney in Asia, Again Raymond H. Lopez Pace University Follow this and additional works at: http://digitalcommons.pace.edu/business_cases Part of the Banking and Finance Commons Recommended Citation Lopez, Raymond H., Disney in Asia, Again (2002). Case Studies. Paper 3. http://digitalcommons.pace.edu/business_cases/3 This Article is brought to you for free and open access by the Lubin School ofRead MoreRooms Division Operation Management21324 Words à |à 86 Pagesin a hotel. 45 2.1.2: What is the meant by back of the house and front of the house? 45 2.1.3: The Different department of the front of the house area. 45 2.1.4 How the Front of the house area helps in the effective management of rooms division? 45 2.2 Discuss the key aspects of planning and management of the front of the house area for onr of the chosen organization (2.2). Apply relevant theories and a range of methods and techniques in the discussion analyzing the department plan, workingRead MoreRooms Division Operation Management21324 Words à |à 86 Pagessections in a hotel. 45 2.1.2: What is the meant by back of the house and front of the house? 45 2.1.3: The Different department of the front of the house area. 45 2.1.4 How the Front of the house area helps in the effective management of rooms division? 45 2.2 Discuss the key aspects of planning and management of the front of the house area for onr of the chosen organization (2.2). Apply relevant theories and a range of methods and techniques in the discussion analyzing the department plan, working
Monday, December 16, 2019
A Story of an entrepreneur Free Essays
Entrepreneur is an individual who organizes and operates a business and taking financial risk to do so. The entrepreneur is commonly seen as an innovator of new ideas, and business processes. Everyone has different strengths and weaknesses ,and entrepreneurs are no exception. We will write a custom essay sample on A Story of an entrepreneur or any similar topic only for you Order Now But all entrepreneurs share certain qualities. We all know about Md. Yuanââ¬â¢s, Salmon F. Raman, Bill gates, Richard Brannon and so on. They create such a miracle in the world as an entrepreneur. But now we are talking about a person who is not such popular like hem; but he an real life entrepreneur He earns very low but he can be the great example for us or those who wants to be an entrepreneur. His name is Md Kafka All, An entrepreneur. He is a freedom fighter and now he is a hawker of Goulash Hawkers Market ,make his earnings by selling cloth products like T-shirts, pant, childrenââ¬â¢s outfits and other materials. He was born in 1950 in National at Lakehurst district in Islanders village . He is the youngest son of Mohammad All and Nazism statue. From childhood he was familiar with poverty and at very early GE he lost his parentââ¬â¢s. Md. Kafka all is not an educated person at all. He Just went to school only for one day!!!!! And that day he decided that he will never come to school again!!! But this fact canââ¬â¢t beat his confidence. In 1971, he participated in the war. After that 9 month bloodshed war. He lost everything. He had nothing to do at that time. So he took a loan of only 500 take from a relative and then came in Dacha 1975 . He didnââ¬â¢t have any plan or idea. He didnââ¬â¢t knew his destination. But he had only one thing and that is courage and self-confidence. He slowly made connections everywhere. He met as many people as he could and bullied up relationships. Afterwards, this people helped him. They took him to guiltiest and attached him how to do his business. From that day he started a new life. Then he started his business by a rickshaw van from one area to another to sell his product like T-shirts, pant, childrenââ¬â¢s outfits and other materials. Then after some time he rented a small shop with his product in sultana. It is true that Kafka all is not as popular as the other entrepreneur but now he is much solvent. Now he is the owner of his own shop in the goulash hawkers market he is very much popular for his honesty. He usually opens his shop at 9:00 am and finishes his work 10:00 pm. So he works for 14 hours a day,but in the seasonal times like Did he works for almost 20 hours daily. Beside him,his grandson helps him to work. Basically,there is only one employee working in the shop but in seasonal times he hires 4 employees by working in two shifts and he pays 3000 take to each employees and also provides food and shelter to them. He also give them performance bonuses so that they get motivated to attract more customers. He rations the bonus by the number of products sold by an individual employee. He maximizes his profit in the winter season;This is peak time he sells his product the most. He also makes a handsome amount of profit in the national festivals like Did LU flirt and Durra Pupas. He incurred a severe loss when there is a hart. Hart interrupts his daily business routine. Let is quite impossible for him to various places. He mainly asks for people from his relatives and brings employees room his village. He expects good behavior from them so that they can deal with customers effectively. Elf they fails to maintain this,he fires them out. He expects honesty and loyalty from the employees. From Sultana and Maryanne,Saber All brings all his Readmes garment products. He had many dealers and keep regular contact with them, and bought good from them. Very rarely he buys the goods on cash but most of the times he buys them on account. His daily sales revenue is equivalent to 2000 to 3000 Take and from there he makes a profit of 700 to 900 Take. He states that he is quite happy with the profit he makes. The customers mainly comes to his shop because he charges less then the other shoppers which sit Just beside his shop. He attracts the customers by the diversity of the products. The most interesting fact is his main customers are not the lower class people but the higher class ones from the trip-state area like Goulash and Banana?and they are the regular ones!! He gave an advice to us about what a person need to be if he [she wants to be an entrepreneur. He states that every entrepreneur must believe in himself. One should maintain honesty and believe in the decisions he make. He notes that without honesty no one can succeed in life. One should be hardworking to achieve the goal of the business. We should salute and respect this Freedom fighter because instead of all this ups and downs he never gave up. He continued his business even after incurring a loss. He has tremendous self confidence which made him able to run the business for 38 years. That is what a true entrepreneur have to have. How to cite A Story of an entrepreneur, Papers
Sunday, December 8, 2019
Of regiment of health Essay Example For Students
Of regiment of health Essay There is a wisdom in this; beyond the rules of physic: a mans own observation, what he finds good of, and what he finds hurt of, is the best physic to preserve health. But it is a safer conclusion to say, This agreeth not well with me, therefore, I will not continue it; than this, I find no offence of this, therefore I may use it. For strength of nature in youth, passeth over many excesses, which are owing a man till his age. Discern of the coming on of years, and think not to do the same things still; for age will not be defied. Beware of sudden change, in any great point of diet, and, if necessity inforce it, fit the rest to it. For it is a secret both in nature and state, that it is safer to change many things, than one. Examine thy customs of diet, sleep, exercise, apparel, and the like; and try, in any thing thou shalt judge hurtful, to discontinue it, by little and little; but so, as if thou dost find any inconvenience by the change, thou come back to it again: for it is hard to distinguish that which is generally held good and wholesome, from that which is good particularly, and fit for thine own body. To be free-minded and cheerfully disposed, at hours of meat, and of sleep, and of exercise, is one of the best precepts of long lasting. As for the passions, and studies of the mind; avoid envy, anxious fears; anger fretting inwards; subtle and knotty inquisitions; joys and exhilarations in excess; sadness not communicated. Entertain hopes; mirth rather than joy; variety of delights, rather than surfeit of them; wonder and admiration, and therefore novelties; studies that fill the mind with splendid and illustrious objects, as histories, fables, and contemplations of nature. If you fly physic in health altogether, it will be too strange for your body, when you shall need it. If you make it too familiar, it will work no extraordinary effect, when sickness cometh. I commend rather some diet for certain seasons, than frequent use of physic, except it be grown into a custom. For those diets alter the body more, and trouble it less. Despise no new accident in your body, but ask opinion of it. In sickness, respect health principally; and in health, action. For those that put their bodies to endure in health, may in most sicknesses, which are not very sharp, be cured only with diet, and tendering. Celsus could never have spoken it as a physician, had he not been a wise man withal, when he giveth it for one of the great precepts of health and lasting, that a man do vary, and interchange contraries, but with an inclination to the more benign extreme: use fasting and full eating, but rather full eating; watching and sleep, but rather sleep; sitting and exercise, but rather exercise; and the like. So shall nature be cherished, and yet taught masteries. Physicians are, some of them, so pleasing and conformable to the humor of the patient, as they press not the true cure of the disease; and some other are so regular, in proceeding according to art for the disease, as they respect not sufficiently the condition of the patient. Take one of a middle temper; or if it may not be found in one man, combine two of either sort; and forget not to call as well, the best acquainted with your body, as the best reputed of for his faculty.
Saturday, November 30, 2019
The Theory of Human Caring Essay Example
The Theory of Human Caring Paper Jean Watsonââ¬â¢s Theory of Human Caring represents a dramatic paradigm shift, and as a result, it has been a source of great controversy since its introduction. The purpose of this paper is to discuss the comprehension of the theory, the implications of caring, and the application of the theory to practice in an attempt to show that the Theory of Human Caring is valuable to the nursing profession. Sources include published literature, including the work of Jean Watson. Jean Watsonââ¬â¢s Theory of Human Caring: Is It Valuable to the Profession of Nursing? Jean Watsonââ¬â¢s Theory of Human Caring represents a dramatic paradigm shift, and as a result, it has been a source of great controversy since its introduction. It is still a relatively new theory, with the first publication in 1979 in Watsonââ¬â¢s book Nursing: The Philosophy and Science of Caring. Possibly due to its newness, there is still much debate over the ease of comprehension of her work, the implications of caring within her theory, and whether her theory is applicable to nursing practice in todayââ¬â¢s world of advanced technology and budget cuts. We will write a custom essay sample on The Theory of Human Caring specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on The Theory of Human Caring specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on The Theory of Human Caring specifically for you FOR ONLY $16.38 $13.9/page Hire Writer This paper will explore each of these issues regarding the theory, and attempt to demonstrate that Watsonââ¬â¢s Theory of Human Caring definitely has a place in nursing practice today. A Summary of Jean Watsonââ¬â¢s Theory of Human Caring Jean Watson views nursing as an art and a science, which has the goal of preserving the worth of humankind through the process of caring. Caring is seen as the essence of nursing and a moral ideal: Caringâ⬠¦has to become a will, an intention, a commitment, and a conscious judgment that manifests itself in concrete acts. Human care, as a moral ideal, also transcends the act and goes beyond the specific act of an individual nurse and produces collective acts of the nursing profession that have important consequences for human civilization (Watson, 1988, p. 32). Also, Watson stresses the subjectivity of the human experience, and uses the term phenomenal field to describe a personââ¬â¢s individual frame of reference, which is influenced by past experiences and can never be truly known by another person. Anotheraspect of Watsonââ¬â¢s theory is transpersonal caring, in which nurse and patient coparticipate in the goal of achieving health (Watson, 1988, p. 70). Watson (1988) defines health as harmony between mind, body and soul, and illness as a subjective disharmony between mind, body, and soul. As well, integral to Watsonââ¬â¢s theory are the 10 carative factors that serve as a ââ¬Å"framework for providing a structure and order for nursing phenomenaâ⬠(Watson, 1997, p. 50). The 10 carative factors are as follows: 1) Humanistic-altruistic system of values 2) Faith-hope 3) Sensitivity to self and others 4) Helping-trusting, human care relationship 5) Expressing positive and negative feelings 6) Creative problem-solving caring process 7) Transpersonal teaching-learning 8) Supportive, protective, and/or corrective mental, physical, societal, and spiritual environment 9) Human needs assistance 10) Existential-phenomenological-spiritual forces. All of this is presupposed by a knowledge base and clinical competence (Watson, 1988, p. 75). Watson (1988) believes that nursing must separate itself from the reductionistic views of the traditional science medical paradigm and focus on movement towards a human science nursing paradigm. Watson also readily acknowledges that her theory is a work in progress, and she ââ¬Å"invites participants to co-create the modelââ¬â¢s furtheremergenceâ⬠(Watson, 1997, p. 52). This is in accordance with her theory in that she believes that everything is in an unending process of becoming (Watson, 1988). Discussion of The Theory of Human Caring Comprehension Watsonââ¬â¢s Theory of Caring has been influenced by a variety of disciplines outside of nursing. For example, Watson (1997) acknowledged that aspects of psychology, existential-phenomenological philosophy, and metaphysics helped to mold her theory. As a result, authors such as Cohen (1991) and Barnhart et al. (as cited in McCance, McKenna, Boore, 1999) believe that one must have background knowledge of these disciplines in order to fully understand Watsonââ¬â¢s theory. Furthermore, it has been suggested that nurses may not possess this knowledge (McCance et al. , 1999), which may make the theory less appealing. To expand, McKenna (as cited in McCance et al. , 1999) stated that ââ¬Å"theory should be easily understood if it is to gain the attention and commitment of hard pressed cliniciansâ⬠(p. 1393). However, it must be stated that nurses should not be viewed as incapable of acquiring knowledge in disciplines such as psychology and philosophy. As well, the application of Watsonââ¬â¢s theory in a variety of different areas of nursing (which will be discussed later in this paper) suggests that nurses have been able to utilize the theory successfully, regardless of educational background. Watson has also been criticized for using language and concepts in her model that are difficult to understand (Barker Reynolds, as cited in Sourial, 1996), which has the potential to limit the theoryââ¬â¢s success. Sourial (1996) found that Watson frequently substituted different terms for the same idea without explanation, leading to confusion (i. e. , caring transaction, caring moment and caring occasion are equivalent terms). Sourial(1996) suggested that using ââ¬Å"consistent terminologyâ⬠¦[and] additional diagrams would help to clarify and make her [Watsonââ¬â¢s] theory more conciseâ⬠(p. 403). Conversely, Walker (1996) argued that Watson ââ¬Å"explain[s] abstract phenomena by using ordinary language in extraordinary waysâ⬠(p. 992), and that she ââ¬Å" weaves concepts and ideas together with the elegant simplicity of a work of literatureâ⬠(p. 993). Furthermore, students of the College of Nursing in London who were taught to use the Theory of Human Caring, ââ¬Å"found the language in Watsonââ¬â¢s model difficult, describing it as ââ¬ËAmericanââ¬â¢ at first, but they were quickly able to find examples from their experience and use Watsonââ¬â¢s concepts skillfully and fluentlyâ⬠(Allan, 1996, p. 43). It is easy to see from the above sources that the perceived difficulty of Watsonââ¬â¢s language is a subjective experience.
Tuesday, November 26, 2019
Ten Things to Know About North Korea
Ten Things to Know About North Korea The country of North Korea has been in the news frequently in recent years due to its uneasy relationship with the international community. However, few people know much about North Korea. For example, its full name is The Democratic Peoples Republic of North Korea. This article provides facts such as these to give an introduction into the ten most important things about North Korea in an effort to geographically educate readers on the country. 1. The country of North Korea is located on the northern part of the Korean Peninsula which extends the Korea Bay and the Sea of Japan. It is south of China and north of South Korea and occupies roughly 46,540 square miles (120,538 square km) or is slightly smaller than the state of Mississippi. 2. North Korea is separated from South Korea via a ceasefire line that was set along the 38th parallel after the end of the Korean War. It is separated from China by the Yalu River. 3. Terrain in North Korea consists mainly of mountains and hills that are separated by deep, narrow river valleys. The highest peak in North Korea, the volcanic Baekdu Mountain, is found in the northeastern portion of the country at 9,002 feet (2,744 m). Coastal plains are also prominent in the western portion of the country and this area is the main center of agriculture in North Korea. 4. North Koreas climate is temperate with the majority of its rainfall concentrated in the summer. 5. The population of North Korea as of July 2009 was 22,665,345, with a population density of 492.4 persons per square mile (190.1 per sq km) and a median age of 33.5 years. Life expectancy in North Korea is 63.81 years and has fallen in recent years due to famine and lack of medical care. 6. The predominant religions in North Korea are Buddhist and Confucian (51%), traditional beliefs like Shamanism are 25%, while Christians make up 4% of the population and the remaining North Koreans consider themselves as other followers of other religions. In addition, there are government-sponsored religious groups in North Korea. The literacy rate in North Korea is 99%. 7. The capital of North Korea is Pyongyang which is also its largest city. North Korea is a communist state with a single legislative body called the Supreme Peoples Assembly. The country is divided into nine provinces and two municipalities. 8. North Koreas current chief of state is Kim Jong-Il. He has been in that position since July 1994, however, his father, Kim Il-Sung has been named North Koreas eternal president. 9 North Korea gained its independence on August 15, 1945 during the Korean liberation from Japan. On September 9, 1948 the Democratic Peoples Republic of North Korea was established when it became a separate communist country and after the end of the Korean War, North Korea became a closed totalitarian country, focused on self-reliance to limit outside influences. 10. Because North Korea is focused on self-reliance and is closed to outside countries, more than 90% of its economy is controlled by the government and 95% of the goods produced in North Korea are manufactured by state-owned industries. This has caused development and human rights issues to arise in the country. The main crops in North Korea are rice, millet and other grains while industry focuses on the production of military weapons, chemicals, and the mining of minerals like coal, iron ore, graphite and copper. To learn more about North Korea read North Korea - Facts and History on the Asian History GuideSite at About.com and visit the North Korea Geography and Maps page here at Geography at About.com. References Central Intelligence Agency. (2010, April 21). CIA - The World Factbook North Korea. Retrieved from: https://www.cia.gov/library/publications/the-world-factbook/geos/kn.html Infoplease.com. (n.d.). Korea, North: History, Geography, Government, and Culture - Infoplease.com. Retrieved from: infoplease.com/ipa/A0107686.html Wikipedia. (2010, April 23). North Korea - Wikipedia, the Free Encyclopedia. Retrieved from: http://en.wikipedia.org/wiki/North_Korea United States Department of State. (2010, March). North Korea (03/10). Retrieved from: state.gov/r/pa/ei/bgn/2792.htm
Friday, November 22, 2019
3 Fun And Common French Idioms With Animals
3 Fun And Common French Idioms With Animals French idioms are fun and so useful to express a whole concept in a short sentence - here are three common ones, using hens, a bear, and a Spanish cow! Quand Les Poules Auront Des Dents Literally, this means when hens have teeth.à So it means that there is not a chance of this ever happening. The equivalent English idiom is ââ¬Å"when pigs flyâ⬠. Pigs, hensâ⬠¦ itââ¬â¢s all in the barnyard!à Moi, sortir avec Paula ? Quand les poules auront des dents!!Me, going out with Paula? When pigs fly! Il Ne Faut Pas Vendre La Peau De Lââ¬â¢Ours Avant de Lââ¬â¢Avoir Tuà © You shouldnââ¬â¢t sell the bearââ¬â¢s skin before you killed it (the bear). Note the pronunciation of ââ¬Å"un oursâ⬠- un noors. There is a strong liaison in N, and the final S of ours is pronounced. This idiom is easy to understand in French - it means you should not count on the benefit of an action before you have done it. The equivalent English idiom is ââ¬Å"donââ¬â¢t count your chickens before theyââ¬â¢re hatched. With both English and French idiom, itââ¬â¢s not uncommon to leave out part of the sentence: il ne faut pas vendre la peau de lââ¬â¢ours (avant de lââ¬â¢avoir tuà ©). Donââ¬â¢t count your chickens (before they hatch). Comment à §a? Tu vas acheter une voiture avec lââ¬â¢argent que tu vas gagner au loto ? Attends un peu, il ne faut pas vendre la peau de lââ¬â¢ours avant de lââ¬â¢avoir tuà © ! Come again? You are going to buy a car with the money youââ¬â¢ll win at the lottery? Wait a second, dontà count your chickens before they hatch! Parler Franà §ais Comme Une Vache Espagnole Literally, this means to speak French like a Spanish cow. Well, a cow doesnââ¬â¢t speak French to start with, so imagine a Spanish one! This means to speak French very poorly.à The origins of these expressions are unclear, although itââ¬â¢s been in our language since 1640! Some say it comes from ââ¬Å"un basque Espagnolâ⬠- referring to the Basque language. Another theory is just that in older French, both vache and espagnole where pejorative terms. So combine both, and it makes quite an insult.à Nowadays, itââ¬â¢s not that bad, but donââ¬â¢t use it lightly stillâ⬠¦ Ãâ¡a fait 5 ans que Peter apprend le franà §ais, mais il parle comme une vache espagnole : son accent est si fort quââ¬â¢on ne comprend pas un mot de ce quââ¬â¢il dit. Peter has been learning French for five years, but he speaks terrible French: his accent is so strong that you cannot understand a word he says.
Wednesday, November 20, 2019
GENETICS Huntington's Disease MUST HAVE BIOLOGY BACKGROUND Essay
GENETICS Huntington's Disease MUST HAVE BIOLOGY BACKGROUND - Essay Example But as this molecular cartography advances, clinical medicine is turning topsy-turvy in its wake. Huntingtons disease is an autosomal dominant neurodegenerative disease. Appearing usually in the third or fourth decade of life, it can begin in early childhood or old age. A triad of disturbances is pathognomonic: uncontrolled involuntary movements usually including chorea, intellectual decline, and psychiatric disturbance, mostly depression. The disease progresses for twenty years toward an inevitably fatal outcome, and therapy is palliative at best. Families, scientists, and clinicians involved with research on or treatment of Huntingtons disease have been .aware that their development of counseling and diagnostic program using DNA markers could be as precedent-setting as the discovery of the marker itself. They have been trying to act with caution and sensitivity, at the same time making the test available. The Tests offered. Presymptomatic and prenatal testing can now be carried out with a number of different markers to enable risks to be changed from 50 percent to 96 percent or higher of being positive or negative for the gene of Huntingtons disease. Even though there has been some uncertainty as to the exact location of the gene within the most telomeric band on chromosome 4, there are sufficient markers to alter a persons risk significantly if a family is genetically informative. Initially, less than half of all families listed on the National Huntingtons Disease Roster at Indiana University had such an appropriate structure. Owing to the increased informativeness of recently developed markers, recent estimates suggest that up to 75 percent of individuals coming for testing will be found to have genetically informative families. Prenatal Diagnosis. Two types of prenatal diagnostic tests are available: 1) a non-disclosing prenatal or "exclusion test," and 2) a fully disclosing diagnostic test. In a
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